000 02045 a2200601 4500
005 20250518074203.0
264 0 _c20200312
008 202003s 0 0 eng d
022 _a1768-3254
024 7 _a10.1016/j.ejmech.2019.111913
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYang, Gui-Xiang
245 0 0 _aDesign, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents.
_h[electronic resource]
260 _bEuropean journal of medicinal chemistry
_cFeb 2020
300 _a111913 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAging
_xdrug effects
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aAmyloid beta-Peptides
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aAnti-Inflammatory Agents, Non-Steroidal
_xchemical synthesis
650 0 4 _aAstrocytes
_xdrug effects
650 0 4 _aCarbamates
_xchemical synthesis
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aDiosgenin
_xchemical synthesis
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Design
650 0 4 _aGalactose
_xadministration & dosage
650 0 4 _aHumans
650 0 4 _aInflammation
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred ICR
650 0 4 _aMolecular Structure
650 0 4 _aNeuroprotective Agents
_xchemical synthesis
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aProtein Aggregates
_xdrug effects
650 0 4 _aStructure-Activity Relationship
700 1 _aHuang, Yan
700 1 _aZheng, Lu-Lu
700 1 _aZhang, Li
700 1 _aSu, Lin
700 1 _aWu, Yu-Hang
700 1 _aLi, Jie
700 1 _aZhou, Li-Cheng
700 1 _aHuang, Jin
700 1 _aTang, Yun
700 1 _aWang, Rui
700 1 _aMa, Lei
773 0 _tEuropean journal of medicinal chemistry
_gvol. 187
_gp. 111913
856 4 0 _uhttps://doi.org/10.1016/j.ejmech.2019.111913
_zAvailable from publisher's website
999 _c30420992
_d30420992