000 02066 a2200601 4500
005 20250518071204.0
264 0 _c20210729
008 202107s 0 0 eng d
022 _a1522-9653
024 7 _a10.1016/j.joca.2019.11.002
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSharma, N
245 0 0 _aInflammation and joint destruction may be linked to the generation of cartilage metabolites of ADAMTS-5 through activation of toll-like receptors.
_h[electronic resource]
260 _bOsteoarthritis and cartilage
_c05 2020
300 _a658-668 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aADAMTS5 Protein
_xdrug effects
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAggrecans
_xmetabolism
650 0 4 _aBlotting, Western
650 0 4 _aCartilage, Articular
_xdrug effects
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aIn Vitro Techniques
650 0 4 _aInflammation
_xmetabolism
650 0 4 _aInterleukin-6
_xmetabolism
650 0 4 _aLipid A
_xpharmacology
650 0 4 _aLipopeptides
_xpharmacology
650 0 4 _aMale
650 0 4 _aMatrix Metalloproteinase 3
_xdrug effects
650 0 4 _aMiddle Aged
650 0 4 _aOligopeptides
_xpharmacology
650 0 4 _aSingle-Domain Antibodies
_xpharmacology
650 0 4 _aSynovial Membrane
_xdrug effects
650 0 4 _aToll-Like Receptor 2
_xagonists
650 0 4 _aToll-Like Receptor 4
_xagonists
650 0 4 _aToll-Like Receptor 9
_xagonists
650 0 4 _aTumor Necrosis Factor-alpha
_xpharmacology
700 1 _aDrobinski, P
700 1 _aKayed, A
700 1 _aChen, Z
700 1 _aKjelgaard-Petersen, C F
700 1 _aGantzel, T
700 1 _aKarsdal, M A
700 1 _aMichaelis, M
700 1 _aLadel, C
700 1 _aBay-Jensen, A C
700 1 _aLindemann, S
700 1 _aThudium, C S
773 0 _tOsteoarthritis and cartilage
_gvol. 28
_gno. 5
_gp. 658-668
856 4 0 _uhttps://doi.org/10.1016/j.joca.2019.11.002
_zAvailable from publisher's website
999 _c30319890
_d30319890