000 01552 a2200421 4500
005 20250518070517.0
264 0 _c20210217
008 202102s 0 0 eng d
022 _a1090-2120
024 7 _a10.1016/j.bioorg.2019.103403
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYeong, Keng Yoon
245 0 0 _aDiscovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor.
_h[electronic resource]
260 _bBioorganic chemistry
_c01 2020
300 _a103403 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents, Phytogenic
_xchemistry
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Discovery
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aEnzyme Inhibitors
_xchemistry
650 0 4 _aGarcinia mangostana
_xchemistry
650 0 4 _aHumans
650 0 4 _aMolecular Docking Simulation
650 0 4 _aMolecular Structure
650 0 4 _aSirtuin 2
_xantagonists & inhibitors
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTumor Cells, Cultured
650 0 4 _aXanthones
_xchemistry
700 1 _aKhaw, Kooi Yeong
700 1 _aTakahashi, Yukari
700 1 _aItoh, Yukihiro
700 1 _aMurugaiyah, Vikneswaran
700 1 _aSuzuki, Takayoshi
773 0 _tBioorganic chemistry
_gvol. 94
_gp. 103403
856 4 0 _uhttps://doi.org/10.1016/j.bioorg.2019.103403
_zAvailable from publisher's website
999 _c30297937
_d30297937