000 01964 a2200577 4500
005 20250518065742.0
264 0 _c20201029
008 202010s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/s41598-019-52141-5
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKufareva, Irina
245 0 0 _aDiscovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors.
_h[electronic resource]
260 _bScientific reports
_c11 2019
300 _a15893 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdenosine Triphosphate
_xmetabolism
650 0 4 _aBinding Sites
650 0 4 _aCasein Kinase II
_xantagonists & inhibitors
650 0 4 _aCatalytic Domain
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Movement
_xdrug effects
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCrystallography, X-Ray
650 0 4 _aHoloenzymes
_xchemistry
650 0 4 _aHumans
650 0 4 _aKinetics
650 0 4 _aMolecular Docking Simulation
650 0 4 _aPeptides
_xchemistry
650 0 4 _aPhosphorylation
650 0 4 _aProtein Kinase Inhibitors
_xchemistry
650 0 4 _aProtein Subunits
_xantagonists & inhibitors
650 0 4 _aSubstrate Specificity
650 0 4 _aSurface Plasmon Resonance
700 1 _aBestgen, Benoit
700 1 _aBrear, Paul
700 1 _aPrudent, Renaud
700 1 _aLaudet, Béatrice
700 1 _aMoucadel, Virginie
700 1 _aEttaoussi, Mohamed
700 1 _aSautel, Celine F
700 1 _aKrimm, Isabelle
700 1 _aEngel, Matthias
700 1 _aFilhol, Odile
700 1 _aBorgne, Marc Le
700 1 _aLomberget, Thierry
700 1 _aCochet, Claude
700 1 _aAbagyan, Ruben
773 0 _tScientific reports
_gvol. 9
_gno. 1
_gp. 15893
856 4 0 _uhttps://doi.org/10.1038/s41598-019-52141-5
_zAvailable from publisher's website
999 _c30272652
_d30272652