000			02283 a2200661 4500
005			20250518061806.0
264		0	_c20200619
008			202006s 0 0 eng d
022			_a1476-5594
024	7		_a10.1038/s41388-019-1012-2 _2doi
040			_aNLM _beng _cNLM
100	1		_aO'Connor, Caitlin M
245	0	0	_aInactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors. _h[electronic resource]
260			_bOncogene _c01 2020
300			_a703-717 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAmino Acid Substitution
650	0	4	_aArginine _xgenetics
650	0	4	_aCalmodulin-Binding Proteins _xmetabolism
650	0	4	_aCarcinogenesis _xdrug effects
650	0	4	_aCell Line, Tumor
650	0	4	_aDrug Resistance, Neoplasm _xgenetics
650	0	4	_aHumans
650	0	4	_aMAP Kinase Signaling System _xdrug effects
650	0	4	_aMembrane Proteins _xmetabolism
650	0	4	_aMitogen-Activated Protein Kinase Kinases _xantagonists & inhibitors
650	0	4	_aMolecular Dynamics Simulation
650	0	4	_aMutagenesis, Site-Directed
650	0	4	_aMutation
650	0	4	_aNeoplasms _xdrug therapy
650	0	4	_aNerve Tissue Proteins _xmetabolism
650	0	4	_aProtein Kinase Inhibitors _xpharmacology
650	0	4	_aProtein Phosphatase 2 _xgenetics
650	0	4	_aRecombinant Proteins _xgenetics
650	0	4	_aTransfection
650	0	4	_aTyrosine _xgenetics
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aLeonard, Daniel
700	1		_aWiredja, Danica
700	1		_aAvelar, Rita A
700	1		_aWang, Zhizhi
700	1		_aSchlatzer, Daniela
700	1		_aBryson, Benjamin
700	1		_aTokala, Eesha
700	1		_aTaylor, Sarah E
700	1		_aUpadhyay, Aditya
700	1		_aSangodkar, Jaya
700	1		_aGingras, Anne-Claude
700	1		_aWestermarck, Jukka
700	1		_aXu, Wenqing
700	1		_aDiFeo, Analisa
700	1		_aBrautigan, David L
700	1		_aHaider, Shozeb
700	1		_aJackson, Mark
700	1		_aNarla, Goutham
773	0		_tOncogene _gvol. 39 _gno. 3 _gp. 703-717
856	4	0	_uhttps://doi.org/10.1038/s41388-019-1012-2 _zAvailable from publisher's website
999			_c30131668 _d30131668