000 01545 a2200421 4500
005 20250518061356.0
264 0 _c20200303
008 202003s 0 0 eng d
022 _a1878-1454
024 7 _a10.1016/j.bbapap.2019.140281
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBuchholz, Ina
245 0 0 _aThe impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant.
_h[electronic resource]
260 _bBiochimica et biophysica acta. Proteins and proteomics
_c01 2020
300 _a140281 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aDisease Progression
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aMutation
650 0 4 _aPancreatitis
650 0 4 _aProtein Conformation
650 0 4 _aStress, Physiological
650 0 4 _aTemperature
650 0 4 _aTrypsin
_xchemistry
650 0 4 _aTrypsin Inhibitor, Kazal Pancreatic
_xchemistry
700 1 _aNagel, Felix
700 1 _aKlein, Annelie
700 1 _aWagh, Preshit R
700 1 _aMahajan, Ujjwal M
700 1 _aGreinacher, Andreas
700 1 _aLerch, Markus M
700 1 _aMayerle, Julia
700 1 _aDelcea, Mihaela
773 0 _tBiochimica et biophysica acta. Proteins and proteomics
_gvol. 1868
_gno. 1
_gp. 140281
856 4 0 _uhttps://doi.org/10.1016/j.bbapap.2019.140281
_zAvailable from publisher's website
999 _c30116358
_d30116358