000 01777 a2200481 4500
005 20250518061035.0
264 0 _c20200303
008 202003s 0 0 eng d
022 _a1521-0111
024 7 _a10.1124/mol.119.115964
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLee, Tobie D
245 0 0 _aA High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
_h[electronic resource]
260 _bMolecular pharmacology
_c11 2019
300 _a629-640 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Intramural
650 0 4 _aATP Binding Cassette Transporter, Subfamily B
_xmetabolism
650 0 4 _aATP Binding Cassette Transporter, Subfamily B, Member 1
_xchemistry
650 0 4 _aATP Binding Cassette Transporter, Subfamily G, Member 2
_xmetabolism
650 0 4 _aAntineoplastic Agents
_xchemistry
650 0 4 _aCytotoxins
_xchemistry
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aHEK293 Cells
650 0 4 _aHeLa Cells
650 0 4 _aHigh-Throughput Screening Assays
_xmethods
650 0 4 _aHumans
650 0 4 _aNeoplasm Proteins
_xmetabolism
650 0 4 _aSubstrate Specificity
_xdrug effects
700 1 _aLee, Olivia W
700 1 _aBrimacombe, Kyle R
700 1 _aChen, Lu
700 1 _aGuha, Rajarshi
700 1 _aLusvarghi, Sabrina
700 1 _aTebase, Bethilehem G
700 1 _aKlumpp-Thomas, Carleen
700 1 _aRobey, Robert W
700 1 _aAmbudkar, Suresh V
700 1 _aShen, Min
700 1 _aGottesman, Michael M
700 1 _aHall, Matthew D
773 0 _tMolecular pharmacology
_gvol. 96
_gno. 5
_gp. 629-640
856 4 0 _uhttps://doi.org/10.1124/mol.119.115964
_zAvailable from publisher's website
999 _c30106347
_d30106347