000 02148 a2200553 4500
005 20250518055558.0
264 0 _c20210129
008 202101s 0 0 eng d
022 _a1097-4644
024 7 _a10.1002/jcb.29350
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWright, Thomas D
245 0 0 _aPharmacological inhibition of the MEK5/ERK5 and PI3K/Akt signaling pathways synergistically reduces viability in triple-negative breast cancer.
_h[electronic resource]
260 _bJournal of cellular biochemistry
_c02 2020
300 _a1156-1168 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBenzodiazepinones
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Movement
_xdrug effects
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aDrug Synergism
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aMAP Kinase Kinase 5
_xantagonists & inhibitors
650 0 4 _aMitogen-Activated Protein Kinase 7
_xantagonists & inhibitors
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
_xpharmacology
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-akt
_xantagonists & inhibitors
650 0 4 _aPyridones
_xpharmacology
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aPyrimidinones
_xpharmacology
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTriple Negative Breast Neoplasms
_xmetabolism
700 1 _aRaybuck, Christopher
700 1 _aBhatt, Akshita
700 1 _aMonlish, Darlene
700 1 _aChakrabarty, Suravi
700 1 _aWendekier, Katy
700 1 _aGartland, Nathan
700 1 _aGupta, Mohit
700 1 _aBurow, Matthew E
700 1 _aFlaherty, Patrick T
700 1 _aCavanaugh, Jane E
773 0 _tJournal of cellular biochemistry
_gvol. 121
_gno. 2
_gp. 1156-1168
856 4 0 _uhttps://doi.org/10.1002/jcb.29350
_zAvailable from publisher's website
999 _c30055985
_d30055985