000 01890 a2200553 4500
005 20250518055531.0
264 0 _c20200303
008 202003s 0 0 eng d
022 _a1521-0111
024 7 _a10.1124/mol.119.116129
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCao, Zhi-Xing
245 0 0 _aIsoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo.
_h[electronic resource]
260 _bMolecular pharmacology
_c11 2019
300 _a589-599 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aChalcones
_xadministration & dosage
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aEnzyme Inhibitors
_xadministration & dosage
650 0 4 _aFemale
650 0 4 _aGlycyrrhiza
650 0 4 _aHumans
650 0 4 _aLeukemia, Myeloid, Acute
_xdrug therapy
650 0 4 _aMice
650 0 4 _aMice, Inbred NOD
650 0 4 _aMice, SCID
650 0 4 _aMolecular Docking Simulation
_xmethods
650 0 4 _aTreatment Outcome
650 0 4 _aXenograft Model Antitumor Assays
_xmethods
650 0 4 _afms-Like Tyrosine Kinase 3
_xantagonists & inhibitors
700 1 _aWen, Yi
700 1 _aHe, Jun-Lin
700 1 _aHuang, Shen-Zhen
700 1 _aGao, Fei
700 1 _aGuo, Chuan-Jie
700 1 _aLiu, Qing-Qing
700 1 _aZheng, Shu-Wen
700 1 _aGong, Dao-Yin
700 1 _aLi, Yu-Zhi
700 1 _aZhang, Ruo-Qi
700 1 _aChen, Jian-Ping
700 1 _aPeng, Cheng
773 0 _tMolecular pharmacology
_gvol. 96
_gno. 5
_gp. 589-599
856 4 0 _uhttps://doi.org/10.1124/mol.119.116129
_zAvailable from publisher's website
999 _c30054447
_d30054447