000 01468 a2200373 4500
005 20250518052906.0
264 0 _c20200622
008 202006s 0 0 eng d
022 _a1756-8927
024 7 _a10.4155/fmc-2018-0512
_2doi
040 _aNLM
_beng
_cNLM
100 1 _adas Neves, Gustavo Machado
245 0 0 _aTargeting pteridine reductase 1 and dihydrofolate reductase: the old is a new trend for leishmaniasis drug discovery.
_h[electronic resource]
260 _bFuture medicinal chemistry
_c08 2019
300 _a2107-2130 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
650 0 4 _aAnimals
650 0 4 _aAntiprotozoal Agents
_xchemistry
650 0 4 _aDrug Discovery
650 0 4 _aFolic Acid Antagonists
_xchemistry
650 0 4 _aHumans
650 0 4 _aLeishmania
_xdrug effects
650 0 4 _aLeishmaniasis
_xdrug therapy
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aMultienzyme Complexes
_xantagonists & inhibitors
650 0 4 _aOxidoreductases
_xantagonists & inhibitors
650 0 4 _aTetrahydrofolate Dehydrogenase
_xmetabolism
650 0 4 _aThymidylate Synthase
_xantagonists & inhibitors
700 1 _aKagami, Luciano P
700 1 _aGonçalves, Itamar L
700 1 _aEifler-Lima, Vera L
773 0 _tFuture medicinal chemistry
_gvol. 11
_gno. 16
_gp. 2107-2130
856 4 0 _uhttps://doi.org/10.4155/fmc-2018-0512
_zAvailable from publisher's website
999 _c29964672
_d29964672