000 01971 a2200541 4500
005 20250518045855.0
264 0 _c20190909
008 201909s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/s41467-019-10993-5
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNing, Jian-Fang
245 0 0 _aMyc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma.
_h[electronic resource]
260 _bNature communications
_c07 2019
300 _a2910 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntigens, Surface
_xgenetics
650 0 4 _aAtaxia Telangiectasia Mutated Proteins
_xgenetics
650 0 4 _aCell Cycle Proteins
_xgenetics
650 0 4 _aCyclin-Dependent Kinases
_xgenetics
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aFemale
650 0 4 _aGlioblastoma
_xdrug therapy
650 0 4 _aHomologous Recombination
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMice, SCID
650 0 4 _aN-Myc Proto-Oncogene Protein
_xgenetics
650 0 4 _aNeoplastic Stem Cells
_xmetabolism
650 0 4 _aPoly (ADP-Ribose) Polymerase-1
_xgenetics
650 0 4 _aPoly(ADP-ribose) Polymerase Inhibitors
_xadministration & dosage
650 0 4 _aProtein Binding
650 0 4 _aProto-Oncogene Proteins c-myc
_xgenetics
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aStanciu, Monica
700 1 _aHumphrey, Melissa R
700 1 _aGorham, Joshua
700 1 _aWakimoto, Hiroko
700 1 _aNishihara, Reiko
700 1 _aLees, Jacqueline
700 1 _aZou, Lee
700 1 _aMartuza, Robert L
700 1 _aWakimoto, Hiroaki
700 1 _aRabkin, Samuel D
773 0 _tNature communications
_gvol. 10
_gno. 1
_gp. 2910
856 4 0 _uhttps://doi.org/10.1038/s41467-019-10993-5
_zAvailable from publisher's website
999 _c29863244
_d29863244