000 | 02018 a2200553 4500 | ||
---|---|---|---|
005 | 20250518045617.0 | ||
264 | 0 | _c20200727 | |
008 | 202007s 0 0 eng d | ||
022 | _a2451-9448 | ||
024 | 7 |
_a10.1016/j.chembiol.2019.06.003 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aSumi, Natalia J | |
245 | 0 | 0 |
_aDivergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets. _h[electronic resource] |
260 |
_bCell chemical biology _c09 2019 |
||
300 |
_a1240-1252.e11 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAnilides _xpharmacology |
650 | 0 | 4 |
_aAntineoplastic Combined Chemotherapy Protocols _xmetabolism |
650 | 0 | 4 |
_aAurora Kinase B _xmetabolism |
650 | 0 | 4 | _aCell Line, Tumor |
650 | 0 | 4 | _aDrug Discovery |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aLung Neoplasms _xdrug therapy |
650 | 0 | 4 |
_aMAP Kinase Kinase 1 _xmetabolism |
650 | 0 | 4 |
_aMAP Kinase Kinase 2 _xmetabolism |
650 | 0 | 4 |
_aOrganophosphates _xpharmacology |
650 | 0 | 4 | _aPolypharmacology |
650 | 0 | 4 |
_aProtein Kinase Inhibitors _xchemistry |
650 | 0 | 4 |
_aProtein-Tyrosine Kinases _xmetabolism |
650 | 0 | 4 |
_aPyridines _xpharmacology |
650 | 0 | 4 |
_aQuinazolines _xpharmacology |
650 | 0 | 4 |
_aQuinolines _xpharmacology |
650 | 0 | 4 | _aSystems Analysis |
700 | 1 | _aCtortecka, Claudia | |
700 | 1 | _aHu, Qianqian | |
700 | 1 | _aBryant, Annamarie T | |
700 | 1 | _aFang, Bin | |
700 | 1 | _aRemsing Rix, Lily L | |
700 | 1 | _aAyaz, Muhammad | |
700 | 1 | _aKinose, Fumi | |
700 | 1 | _aWelsh, Eric A | |
700 | 1 | _aEschrich, Steven A | |
700 | 1 | _aLawrence, Harshani R | |
700 | 1 | _aKoomen, John M | |
700 | 1 | _aHaura, Eric B | |
700 | 1 | _aRix, Uwe | |
773 | 0 |
_tCell chemical biology _gvol. 26 _gno. 9 _gp. 1240-1252.e11 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.chembiol.2019.06.003 _zAvailable from publisher's website |
999 |
_c29853635 _d29853635 |