| 000 | 01701 a2200481 4500 | ||
|---|---|---|---|
| 005 | 20250518045030.0 | ||
| 264 | 0 | _c20200309 | |
| 008 | 202003s 0 0 eng d | ||
| 022 | _a1098-1004 | ||
| 024 | 7 |
_a10.1002/humu.23848 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aRath, Abhijit | |
| 245 | 0 | 0 |
_aFunctional interrogation of Lynch syndrome-associated MSH2 missense variants via CRISPR-Cas9 gene editing in human embryonic stem cells. _h[electronic resource] |
| 260 |
_bHuman mutation _c11 2019 |
||
| 300 |
_a2044-2056 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aCRISPR-Cas Systems |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 |
_aColorectal Neoplasms, Hereditary Nonpolyposis _xdiagnosis |
| 650 | 0 | 4 | _aDNA Damage |
| 650 | 0 | 4 | _aDNA Repair |
| 650 | 0 | 4 | _aGene Editing |
| 650 | 0 | 4 | _aHigh-Throughput Nucleotide Sequencing |
| 650 | 0 | 4 |
_aHuman Embryonic Stem Cells _xmetabolism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMicrosatellite Instability |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aMutS Homolog 2 Protein _xchemistry |
| 650 | 0 | 4 | _aMutation, Missense |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 | _aSignal Transduction |
| 700 | 1 | _aMishra, Akriti | |
| 700 | 1 | _aFerreira, Victoria Duque | |
| 700 | 1 | _aHu, Chaoran | |
| 700 | 1 | _aOmerza, Gregory | |
| 700 | 1 | _aKelly, Kevin | |
| 700 | 1 | _aHesse, Andrew | |
| 700 | 1 | _aReddi, Honey V | |
| 700 | 1 | _aGrady, James P | |
| 700 | 1 | _aHeinen, Christopher D | |
| 773 | 0 |
_tHuman mutation _gvol. 40 _gno. 11 _gp. 2044-2056 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1002/humu.23848 _zAvailable from publisher's website |
| 999 |
_c29834434 _d29834434 |
||