000 02137 a2200613 4500
005 20250518044957.0
264 0 _c20190705
008 201907s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/s41467-019-10712-0
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAgudelo, Leandro Z
245 0 0 _aSkeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance.
_h[electronic resource]
260 _bNature communications
_c06 2019
300 _a2767 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdaptation, Physiological
650 0 4 _aAnimals
650 0 4 _aAspartate Aminotransferases
_xmetabolism
650 0 4 _aAspartic Acid
_xmetabolism
650 0 4 _aCarbidopa
_xpharmacology
650 0 4 _aCell Respiration
_xdrug effects
650 0 4 _aEnergy Metabolism
_xdrug effects
650 0 4 _aFatigue
_xphysiopathology
650 0 4 _aGlycolysis
_xphysiology
650 0 4 _aKynurenine
_xmetabolism
650 0 4 _aMalates
_xmetabolism
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Knockout
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aModels, Animal
650 0 4 _aMuscle, Skeletal
_xmetabolism
650 0 4 _aPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
_xgenetics
650 0 4 _aPhysical Conditioning, Animal
_xphysiology
650 0 4 _aProtein Isoforms
_xgenetics
650 0 4 _aTransaminases
_xantagonists & inhibitors
700 1 _aFerreira, Duarte M S
700 1 _aDadvar, Shamim
700 1 _aCervenka, Igor
700 1 _aKetscher, Lars
700 1 _aIzadi, Manizheh
700 1 _aZhengye, Liu
700 1 _aFurrer, Regula
700 1 _aHandschin, Christoph
700 1 _aVenckunas, Tomas
700 1 _aBrazaitis, Marius
700 1 _aKamandulis, Sigitas
700 1 _aLanner, Johanna T
700 1 _aRuas, Jorge L
773 0 _tNature communications
_gvol. 10
_gno. 1
_gp. 2767
856 4 0 _uhttps://doi.org/10.1038/s41467-019-10712-0
_zAvailable from publisher's website
999 _c29832459
_d29832459