000 01840 a2200529 4500
005 20250518044927.0
264 0 _c20191104
008 201911s 0 0 eng d
022 _a1768-3254
024 7 _a10.1016/j.ejmech.2019.06.037
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChen, Shulun
245 0 0 _aDesign, synthesis and antitumor study of a series of N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors.
_h[electronic resource]
260 _bEuropean journal of medicinal chemistry
_cOct 2019
300 _a38-55 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAmines
_xchemical synthesis
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Design
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aEnzyme Inhibitors
_xchemical synthesis
650 0 4 _aFemale
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aIndoleamine-Pyrrole 2,3,-Dioxygenase
_xantagonists & inhibitors
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMolecular Structure
650 0 4 _aOxadiazoles
_xchemical synthesis
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aStructure-Activity Relationship
700 1 _aGuo, Wei
700 1 _aLiu, Xiaohua
700 1 _aSun, Pu
700 1 _aWang, Yi
700 1 _aDing, Chunyong
700 1 _aMeng, Linghua
700 1 _aZhang, Ao
773 0 _tEuropean journal of medicinal chemistry
_gvol. 179
_gp. 38-55
856 4 0 _uhttps://doi.org/10.1016/j.ejmech.2019.06.037
_zAvailable from publisher's website
999 _c29830693
_d29830693