000 01673 a2200469 4500
005 20250518043855.0
264 0 _c20191223
008 201912s 0 0 eng d
022 _a1471-2407
024 7 _a10.1186/s12885-019-5788-9
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKümler, Iben
245 0 0 _aTwo open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase I gene.
_h[electronic resource]
260 _bBMC cancer
_cJun 2019
300 _a573 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase II; Journal Article
650 0 4 _aAged
650 0 4 _aAntineoplastic Agents
_xtherapeutic use
650 0 4 _aBiomarkers, Pharmacological
650 0 4 _aBreast Neoplasms
_xdiagnosis
650 0 4 _aDNA Topoisomerases, Type I
_xgenetics
650 0 4 _aDrug Therapy, Combination
650 0 4 _aFemale
650 0 4 _aGene Dosage
650 0 4 _aHumans
650 0 4 _aIrinotecan
_xtherapeutic use
650 0 4 _aMiddle Aged
650 0 4 _aPredictive Value of Tests
650 0 4 _aPrognosis
650 0 4 _aReceptor, ErbB-2
_xmetabolism
650 0 4 _aTopoisomerase I Inhibitors
_xtherapeutic use
650 0 4 _aTrastuzumab
_xtherapeutic use
650 0 4 _aTreatment Outcome
700 1 _aBalslev, Eva
700 1 _aStenvang, Jan
700 1 _aBrünner, Nils
700 1 _aEjlertsen, Bent
700 1 _aJakobsen, Erik Hugger
700 1 _aNielsen, Dorte Lisbet
773 0 _tBMC cancer
_gvol. 19
_gno. 1
_gp. 573
856 4 0 _uhttps://doi.org/10.1186/s12885-019-5788-9
_zAvailable from publisher's website
999 _c29795309
_d29795309