000			02176 a2200613 4500
005			20250518043205.0
264		0	_c20200629
008			202006s 0 0 eng d
022			_a1523-5866
024	7		_a10.1093/neuonc/noz105 _2doi
040			_aNLM _beng _cNLM
100	1		_aIppen, Franziska Maria
245	0	0	_aTargeting the PI3K/Akt/mTOR pathway with the pan-Akt inhibitor GDC-0068 in PIK3CA-mutant breast cancer brain metastases. _h[electronic resource]
260			_bNeuro-oncology _c11 2019
300			_a1401-1411 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aApoptosis
650	0	4	_aBiomarkers, Tumor
650	0	4	_aBrain Neoplasms _xdrug therapy
650	0	4	_aBreast Neoplasms _xdrug therapy
650	0	4	_aCell Cycle
650	0	4	_aCell Proliferation
650	0	4	_aClass I Phosphatidylinositol 3-Kinases _xantagonists & inhibitors
650	0	4	_aFemale
650	0	4	_aGene Expression Regulation, Neoplastic
650	0	4	_aHumans
650	0	4	_aMice
650	0	4	_aMice, Nude
650	0	4	_aMutation
650	0	4	_aPhosphatidylinositol 3-Kinases _xchemistry
650	0	4	_aPiperazines _xpharmacology
650	0	4	_aProtein Kinase Inhibitors _xpharmacology
650	0	4	_aPyrimidines _xpharmacology
650	0	4	_aTOR Serine-Threonine Kinases _xantagonists & inhibitors
650	0	4	_aTumor Cells, Cultured
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aGrosch, Julia Katharina
700	1		_aSubramanian, Megha
700	1		_aKuter, Benjamin Macfarlane
700	1		_aLiederer, Bianca M
700	1		_aPlise, Emile G
700	1		_aMora, Joana Liliana
700	1		_aNayyar, Naema
700	1		_aSchmidt, Stephen Paul
700	1		_aGiobbie-Hurder, Anita
700	1		_aMartinez-Lage, Maria
700	1		_aCarter, Scott L
700	1		_aCahill, Daniel P
700	1		_aWakimoto, Hiroaki
700	1		_aBrastianos, Priscilla Kaliopi
773	0		_tNeuro-oncology _gvol. 21 _gno. 11 _gp. 1401-1411
856	4	0	_uhttps://doi.org/10.1093/neuonc/noz105 _zAvailable from publisher's website
999			_c29772964 _d29772964