000			02261 a2200649 4500
005			20250518040159.0
264		0	_c20200420
008			202004s 0 0 eng d
022			_a2399-3642
024	7		_a10.1038/s42003-019-0397-3 _2doi
040			_aNLM _beng _cNLM
100	1		_aSkinner-Adams, Tina S
245	0	0	_aCyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone. _h[electronic resource]
260			_bCommunications biology _c2019
300			_a166 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAnopheles
650	0	4	_aAntimalarials _xchemistry
650	0	4	_aAtovaquone _xchemistry
650	0	4	_aCyclization _xdrug effects
650	0	4	_aDihydroorotate Dehydrogenase
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDrug Combinations
650	0	4	_aElectron Transport Complex III _xantagonists & inhibitors
650	0	4	_aEnzyme Inhibitors _xchemistry
650	0	4	_aErythrocytes _xdrug effects
650	0	4	_aFolic Acid _xmetabolism
650	0	4	_aHep G2 Cells
650	0	4	_aHumans
650	0	4	_aInhibitory Concentration 50
650	0	4	_aLiver _xdrug effects
650	0	4	_aOxidoreductases Acting on CH-CH Group Donors _xmetabolism
650	0	4	_aPlasmodium berghei _xdrug effects
650	0	4	_aPlasmodium falciparum _xdrug effects
650	0	4	_aProguanil _xanalogs & derivatives
650	0	4	_aSporozoites _xdrug effects
650	0	4	_aTerpenes _xmetabolism
650	0	4	_aTriazines _xchemistry
700	1		_aFisher, Gillian M
700	1		_aRiches, Andrew G
700	1		_aHutt, Oliver E
700	1		_aJarvis, Karen E
700	1		_aWilson, Tony
700	1		_avon Itzstein, Mark
700	1		_aChopra, Pradeep
700	1		_aAntonova-Koch, Yevgeniya
700	1		_aMeister, Stephan
700	1		_aWinzeler, Elizabeth A
700	1		_aClarke, Mary
700	1		_aFidock, David A
700	1		_aBurrows, Jeremy N
700	1		_aRyan, John H
700	1		_aAndrews, Katherine T
773	0		_tCommunications biology _gvol. 2 _gp. 166
856	4	0	_uhttps://doi.org/10.1038/s42003-019-0397-3 _zAvailable from publisher's website
999			_c29671306 _d29671306