000 02065 a2200625 4500
005 20250518035549.0
264 0 _c20191031
008 201910s 0 0 eng d
022 _a1095-9203
024 7 _a10.1126/science.aau0447
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMandal, Rajarsi
245 0 0 _aGenetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response.
_h[electronic resource]
260 _bScience (New York, N.Y.)
_c05 2019
300 _a485-491 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntibodies
_xtherapeutic use
650 0 4 _aDNA Mismatch Repair
_xgenetics
650 0 4 _aGenetic Variation
650 0 4 _aImmunotherapy
_xmethods
650 0 4 _aMelanoma, Experimental
_xgenetics
650 0 4 _aMice
650 0 4 _aMicrosatellite Instability
650 0 4 _aMutS Homolog 2 Protein
_xgenetics
650 0 4 _aMutation
650 0 4 _aNeoplasms
_xgenetics
650 0 4 _aProgrammed Cell Death 1 Receptor
_xantagonists & inhibitors
650 0 4 _aTreatment Outcome
700 1 _aSamstein, Robert M
700 1 _aLee, Ken-Wing
700 1 _aHavel, Jonathan J
700 1 _aWang, Hao
700 1 _aKrishna, Chirag
700 1 _aSabio, Erich Y
700 1 _aMakarov, Vladimir
700 1 _aKuo, Fengshen
700 1 _aBlecua, Pedro
700 1 _aRamaswamy, Apoorva T
700 1 _aDurham, Jennifer N
700 1 _aBartlett, Bjarne
700 1 _aMa, Xiaoxiao
700 1 _aSrivastava, Raghvendra
700 1 _aMiddha, Sumit
700 1 _aZehir, Ahmet
700 1 _aHechtman, Jaclyn F
700 1 _aMorris, Luc Gt
700 1 _aWeinhold, Nils
700 1 _aRiaz, Nadeem
700 1 _aLe, Dung T
700 1 _aDiaz, Luis A
700 1 _aChan, Timothy A
773 0 _tScience (New York, N.Y.)
_gvol. 364
_gno. 6439
_gp. 485-491
856 4 0 _uhttps://doi.org/10.1126/science.aau0447
_zAvailable from publisher's website
999 _c29650828
_d29650828