000 01712 a2200421 4500
005 20250518035430.0
264 0 _c20200416
008 202004s 0 0 eng d
022 _a1557-3125
024 7 _a10.1158/1541-7786.MCR-18-1332
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKurimchak, Alison M
245 0 0 _aIntrinsic Resistance to MEK Inhibition through BET Protein-Mediated Kinome Reprogramming in NF1-Deficient Ovarian Cancer.
_h[electronic resource]
260 _bMolecular cancer research : MCR
_c08 2019
300 _a1721-1734 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aCell Cycle Proteins
_xantagonists & inhibitors
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aDrug Therapy, Combination
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aMAP Kinase Kinase 1
_xantagonists & inhibitors
650 0 4 _aMAP Kinase Signaling System
650 0 4 _aNeurofibromin 1
_xdeficiency
650 0 4 _aOvarian Neoplasms
_xdrug therapy
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aReceptor Protein-Tyrosine Kinases
_xantagonists & inhibitors
650 0 4 _aSignal Transduction
650 0 4 _aTranscription Factors
_xantagonists & inhibitors
650 0 4 _aTumor Cells, Cultured
700 1 _aShelton, Claude
700 1 _aHerrera-Montávez, Carlos
700 1 _aDuncan, Kelly E
700 1 _aChernoff, Jonathan
700 1 _aDuncan, James S
773 0 _tMolecular cancer research : MCR
_gvol. 17
_gno. 8
_gp. 1721-1734
856 4 0 _uhttps://doi.org/10.1158/1541-7786.MCR-18-1332
_zAvailable from publisher's website
999 _c29645916
_d29645916