000 01753 a2200553 4500
005 20250518035341.0
264 0 _c20190513
008 201905s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/s41467-019-09809-3
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTian, Weihua
245 0 0 _aThe glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells.
_h[electronic resource]
260 _bNature communications
_c04 2019
300 _a1785 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCHO Cells
650 0 4 _aCricetinae
650 0 4 _aCricetulus
650 0 4 _aDisease Models, Animal
650 0 4 _aFabry Disease
_xdrug therapy
650 0 4 _aGlycosylation
650 0 4 _aLysosomes
_xenzymology
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aRecombinant Proteins
_xtherapeutic use
650 0 4 _aalpha-Galactosidase
_xtherapeutic use
700 1 _aYe, Zilu
700 1 _aWang, Shengjun
700 1 _aSchulz, Morten Alder
700 1 _aVan Coillie, Julie
700 1 _aSun, Lingbo
700 1 _aChen, Yen-Hsi
700 1 _aNarimatsu, Yoshiki
700 1 _aHansen, Lars
700 1 _aKristensen, Claus
700 1 _aMandel, Ulla
700 1 _aBennett, Eric Paul
700 1 _aJabbarzadeh-Tabrizi, Siamak
700 1 _aSchiffmann, Raphael
700 1 _aShen, Jin-Song
700 1 _aVakhrushev, Sergey Y
700 1 _aClausen, Henrik
700 1 _aYang, Zhang
773 0 _tNature communications
_gvol. 10
_gno. 1
_gp. 1785
856 4 0 _uhttps://doi.org/10.1038/s41467-019-09809-3
_zAvailable from publisher's website
999 _c29642736
_d29642736