| 000 | 01554 a2200469 4500 | ||
|---|---|---|---|
| 005 | 20250518034227.0 | ||
| 264 | 0 | _c20200427 | |
| 008 | 202004s 0 0 eng d | ||
| 022 | _a2375-2548 | ||
| 024 | 7 |
_a10.1126/sciadv.aav3335 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aCai, Yuan | |
| 245 | 0 | 0 |
_aIn vivo genome editing rescues photoreceptor degeneration via a Cas9/RecA-mediated homology-directed repair pathway. _h[electronic resource] |
| 260 |
_bScience advances _c04 2019 |
||
| 300 |
_aeaav3335 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aCRISPR-Cas Systems _xgenetics |
| 650 | 0 | 4 |
_aCyclic Nucleotide Phosphodiesterases, Type 6 _xgenetics |
| 650 | 0 | 4 | _aDNA Repair |
| 650 | 0 | 4 | _aElectroporation |
| 650 | 0 | 4 |
_aGene Editing _xmethods |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Inbred C57BL |
| 650 | 0 | 4 |
_aRec A Recombinases _xmetabolism |
| 650 | 0 | 4 |
_aRetinal Degeneration _xtherapy |
| 650 | 0 | 4 |
_aRetinal Rod Photoreceptor Cells _xmetabolism |
| 650 | 0 | 4 | _aRNA, Guide, CRISPR-Cas Systems |
| 700 | 1 | _aCheng, Tianlin | |
| 700 | 1 | _aYao, Yichuan | |
| 700 | 1 | _aLi, Xiao | |
| 700 | 1 | _aMa, Yuqian | |
| 700 | 1 | _aLi, Lingyun | |
| 700 | 1 | _aZhao, Huan | |
| 700 | 1 | _aBao, Jin | |
| 700 | 1 | _aZhang, Mei | |
| 700 | 1 | _aQiu, Zilong | |
| 700 | 1 | _aXue, Tian | |
| 773 | 0 |
_tScience advances _gvol. 5 _gno. 4 _gp. eaav3335 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1126/sciadv.aav3335 _zAvailable from publisher's website |
| 999 |
_c29604777 _d29604777 |
||