000 01620 a2200445 4500
005 20250518033924.0
264 0 _c20190729
008 201907s 0 0 eng d
022 _a1552-4469
024 7 _a10.1038/s41589-019-0263-0
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aVinyard, Michael E
245 0 0 _aCRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML.
_h[electronic resource]
260 _bNature chemical biology
_c05 2019
300 _a529-539 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aClustered Regularly Interspaced Short Palindromic Repeats
_xdrug effects
650 0 4 _aEnzyme Inhibitors
_xchemistry
650 0 4 _aHistone Demethylases
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aLeukemia, Myeloid, Acute
_xdrug therapy
650 0 4 _aModels, Molecular
650 0 4 _aProto-Oncogene Proteins
_xantagonists & inhibitors
650 0 4 _aRepressor Proteins
_xantagonists & inhibitors
650 0 4 _aSmall Molecule Libraries
_xchemistry
700 1 _aSu, Cindy
700 1 _aSiegenfeld, Allison P
700 1 _aWaterbury, Amanda L
700 1 _aFreedy, Allyson M
700 1 _aGosavi, Pallavi M
700 1 _aPark, Yongho
700 1 _aKwan, Eugene E
700 1 _aSenzer, Benjamin D
700 1 _aDoench, John G
700 1 _aBauer, Daniel E
700 1 _aPinello, Luca
700 1 _aLiau, Brian B
773 0 _tNature chemical biology
_gvol. 15
_gno. 5
_gp. 529-539
856 4 0 _uhttps://doi.org/10.1038/s41589-019-0263-0
_zAvailable from publisher's website
999 _c29596013
_d29596013