000 02265 a2200661 4500
005 20250518033858.0
264 0 _c20200203
008 202002s 0 0 eng d
022 _a1878-3686
024 7 _a10.1016/j.ccell.2019.03.004
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHinze, Laura
245 0 0 _aSynthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias.
_h[electronic resource]
260 _bCancer cell
_c04 2019
300 _a664-676.e7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aAsparaginase
_xpharmacology
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aGlycogen Synthase Kinase 3 beta
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aJurkat Cells
650 0 4 _aLeukemia
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMice, Inbred NOD
650 0 4 _aMice, Transgenic
650 0 4 _aPolyethylene Glycols
_xpharmacology
650 0 4 _aProteasome Endopeptidase Complex
_xmetabolism
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProtein Stability
650 0 4 _aProteolysis
650 0 4 _aSynthetic Lethal Mutations
650 0 4 _aTHP-1 Cells
650 0 4 _aUbiquitination
650 0 4 _aWnt Signaling Pathway
_xgenetics
650 0 4 _aWnt3A Protein
_xgenetics
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aPfirrmann, Maren
700 1 _aKarim, Salmaan
700 1 _aDegar, James
700 1 _aMcGuckin, Connor
700 1 _aVinjamur, Divya
700 1 _aSacher, Joshua
700 1 _aStevenson, Kristen E
700 1 _aNeuberg, Donna S
700 1 _aOrellana, Esteban
700 1 _aStanulla, Martin
700 1 _aGregory, Richard I
700 1 _aBauer, Daniel E
700 1 _aWagner, Florence F
700 1 _aStegmaier, Kimberly
700 1 _aGutierrez, Alejandro
773 0 _tCancer cell
_gvol. 35
_gno. 4
_gp. 664-676.e7
856 4 0 _uhttps://doi.org/10.1016/j.ccell.2019.03.004
_zAvailable from publisher's website
999 _c29594480
_d29594480