000 01693 a2200469 4500
005 20250518033221.0
264 0 _c20200214
008 202002s 0 0 eng d
022 _a1476-5594
024 7 _a10.1038/s41388-019-0802-x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHounjet, Judith
245 0 0 _aThe anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition.
_h[electronic resource]
260 _bOncogene
_c07 2019
300 _a5457-5468 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAmyloid Precursor Protein Secretases
_xantagonists & inhibitors
650 0 4 _aAntimalarials
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCell Cycle
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aChloroquine
_xpharmacology
650 0 4 _aDNA Damage
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aHumans
650 0 4 _aLigands
650 0 4 _aPrecursor T-Cell Lymphoblastic Leukemia-Lymphoma
_xmetabolism
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aReceptor, Notch1
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
700 1 _aHabets, Roger
700 1 _aSchaaf, Marco B
700 1 _aHendrickx, Tessa C
700 1 _aBarbeau, Lydie M O
700 1 _aYahyanejad, Sanaz
700 1 _aRouschop, Kasper M
700 1 _aGroot, Arjan J
700 1 _aVooijs, Marc
773 0 _tOncogene
_gvol. 38
_gno. 27
_gp. 5457-5468
856 4 0 _uhttps://doi.org/10.1038/s41388-019-0802-x
_zAvailable from publisher's website
999 _c29571828
_d29571828