000			02148 a2200649 4500
005			20250518032430.0
264		0	_c20200203
008			202002s 0 0 eng d
022			_a1476-5551
024	7		_a10.1038/s41375-019-0461-5 _2doi
040			_aNLM _beng _cNLM
100	1		_aChristian, Sven
245	0	0	_aThe novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. _h[electronic resource]
260			_bLeukemia _c10 2019
300			_a2403-2415 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xpharmacology
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aCell Differentiation _xdrug effects
650	0	4	_aCell Line, Tumor
650	0	4	_aDihydroorotate Dehydrogenase
650	0	4	_aEnzyme Inhibitors _xpharmacology
650	0	4	_aFemale
650	0	4	_aHL-60 Cells
650	0	4	_aHumans
650	0	4	_aLeukemia, Myeloid, Acute _xdrug therapy
650	0	4	_aLeukemia, Promyelocytic, Acute _xdrug therapy
650	0	4	_aMice
650	0	4	_aMice, Inbred NOD
650	0	4	_aMice, SCID
650	0	4	_aOxidoreductases Acting on CH-CH Group Donors _xantagonists & inhibitors
650	0	4	_aPyrimidines _xmetabolism
650	0	4	_aTHP-1 Cells
650	0	4	_aTranslocation, Genetic _xdrug effects
700	1		_aMerz, Claudia
700	1		_aEvans, Laura
700	1		_aGradl, Stefan
700	1		_aSeidel, Henrik
700	1		_aFriberg, Anders
700	1		_aEheim, Ashley
700	1		_aLejeune, Pascale
700	1		_aBrzezinka, Krzysztof
700	1		_aZimmermann, Katja
700	1		_aFerrara, Steven
700	1		_aMeyer, Hanna
700	1		_aLesche, Ralf
700	1		_aStoeckigt, Detlef
700	1		_aBauser, Marcus
700	1		_aHaegebarth, Andrea
700	1		_aSykes, David B
700	1		_aScadden, David T
700	1		_aLosman, Julie-Aurore
700	1		_aJanzer, Andreas
773	0		_tLeukemia _gvol. 33 _gno. 10 _gp. 2403-2415
856	4	0	_uhttps://doi.org/10.1038/s41375-019-0461-5 _zAvailable from publisher's website
999			_c29545553 _d29545553