000 01733 a2200517 4500
005 20250518032012.0
264 0 _c20190503
008 201905s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/s41467-019-09358-9
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSimonetta, Kyle R
245 0 0 _aProspective discovery of small molecule enhancers of an E3 ligase-substrate interaction.
_h[electronic resource]
260 _bNature communications
_c03 2019
300 _a1402 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Binding
_xdrug effects
650 0 4 _aProteolysis
_xdrug effects
650 0 4 _aSmall Molecule Libraries
_xanalysis
650 0 4 _aSubstrate Specificity
_xdrug effects
650 0 4 _aUbiquitin-Protein Ligases
_xmetabolism
650 0 4 _aUbiquitination
_xdrug effects
650 0 4 _abeta Catenin
_xmetabolism
650 0 4 _abeta-Transducin Repeat-Containing Proteins
_xmetabolism
700 1 _aTaygerly, Joshua
700 1 _aBoyle, Kathleen
700 1 _aBasham, Stephen E
700 1 _aPadovani, Chris
700 1 _aLou, Yan
700 1 _aCummins, Thomas J
700 1 _aYung, Stephanie L
700 1 _avon Soly, Szerenke Kiss
700 1 _aKayser, Frank
700 1 _aKuriyan, John
700 1 _aRape, Michael
700 1 _aCardozo, Mario
700 1 _aGallop, Mark A
700 1 _aBence, Neil F
700 1 _aBarsanti, Paul A
700 1 _aSaha, Anjanabha
773 0 _tNature communications
_gvol. 10
_gno. 1
_gp. 1402
856 4 0 _uhttps://doi.org/10.1038/s41467-019-09358-9
_zAvailable from publisher's website
999 _c29531683
_d29531683