000 01906 a2200529 4500
005 20250518024931.0
264 0 _c20200207
008 202002s 0 0 eng d
022 _a1538-7445
024 7 _a10.1158/0008-5472.CAN-18-2711
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHayes, Tikvah K
245 0 0 _aA Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma.
_h[electronic resource]
260 _bCancer research
_c05 2019
300 _a2352-2366 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
650 0 4 _aCell Cycle Checkpoints
650 0 4 _aCell Proliferation
650 0 4 _aCyclin-Dependent Kinase 4
_xantagonists & inhibitors
650 0 4 _aCyclin-Dependent Kinase 6
_xantagonists & inhibitors
650 0 4 _aDrug Resistance, Neoplasm
_xgenetics
650 0 4 _aGTP Phosphohydrolases
_xgenetics
650 0 4 _aHumans
650 0 4 _aMAP Kinase Kinase 1
_xantagonists & inhibitors
650 0 4 _aMAP Kinase Kinase 2
_xantagonists & inhibitors
650 0 4 _aMelanoma
_xdrug therapy
650 0 4 _aMembrane Proteins
_xgenetics
650 0 4 _aMutation
650 0 4 _aPhosphorylation
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTumor Cells, Cultured
700 1 _aLuo, Flora
700 1 _aCohen, Ofir
700 1 _aGoodale, Amy B
700 1 _aLee, Yenarae
700 1 _aPantel, Sasha
700 1 _aBagul, Mukta
700 1 _aPiccioni, Federica
700 1 _aRoot, David E
700 1 _aGarraway, Levi A
700 1 _aMeyerson, Matthew
700 1 _aJohannessen, Cory M
773 0 _tCancer research
_gvol. 79
_gno. 9
_gp. 2352-2366
856 4 0 _uhttps://doi.org/10.1158/0008-5472.CAN-18-2711
_zAvailable from publisher's website
999 _c29426941
_d29426941