000 02500 a2200733 4500
005 20250518024335.0
264 0 _c20200713
008 202007s 0 0 eng d
022 _a1932-7420
024 7 _a10.1016/j.cmet.2019.01.020
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHarris, Isaac S
245 0 0 _aDeubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.
_h[electronic resource]
260 _bCell metabolism
_c05 2019
300 _a1166-1181.e6 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aA549 Cells
650 0 4 _aAminopyridines
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aAntioxidants
_xmetabolism
650 0 4 _aButhionine Sulfoximine
_xpharmacology
650 0 4 _aCatalytic Domain
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aDeubiquitinating Enzymes
_xantagonists & inhibitors
650 0 4 _aFemale
650 0 4 _aGlutamate-Cysteine Ligase
_xantagonists & inhibitors
650 0 4 _aGlutathione
_xmetabolism
650 0 4 _aHumans
650 0 4 _aMCF-7 Cells
650 0 4 _aMammary Glands, Animal
_xcytology
650 0 4 _aMammary Glands, Human
_xcytology
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Nude
650 0 4 _aOrganoids
_xdrug effects
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aProteostasis
_xdrug effects
650 0 4 _aThiocyanates
_xpharmacology
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aUbiquitinated Proteins
_xmetabolism
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aEndress, Jennifer E
700 1 _aColoff, Jonathan L
700 1 _aSelfors, Laura M
700 1 _aMcBrayer, Samuel K
700 1 _aRosenbluth, Jennifer M
700 1 _aTakahashi, Nobuaki
700 1 _aDhakal, Sabin
700 1 _aKoduri, Vidyasagar
700 1 _aOser, Matthew G
700 1 _aSchauer, Nathan J
700 1 _aDoherty, Laura M
700 1 _aHong, Andrew L
700 1 _aKang, Yun Pyo
700 1 _aYounger, Scott T
700 1 _aDoench, John G
700 1 _aHahn, William C
700 1 _aBuhrlage, Sara J
700 1 _aDeNicola, Gina M
700 1 _aKaelin, William G
700 1 _aBrugge, Joan S
773 0 _tCell metabolism
_gvol. 29
_gno. 5
_gp. 1166-1181.e6
856 4 0 _uhttps://doi.org/10.1016/j.cmet.2019.01.020
_zAvailable from publisher's website
999 _c29407069
_d29407069