000 01702 a2200469 4500
005 20250518023815.0
264 0 _c20190312
008 201903s 0 0 eng d
022 _a1553-7358
024 7 _a10.1371/journal.pcbi.1006722
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMarceau West, Rachel
245 0 0 _aIdentifying individual risk rare variants using protein structure guided local tests (POINT).
_h[electronic resource]
260 _bPLoS computational biology
_c02 2019
300 _ae1006722 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAngiopoietin-Like Protein 4
_xgenetics
650 0 4 _aCholesterol Ester Transfer Proteins
_xgenetics
650 0 4 _aComputational Biology
_xmethods
650 0 4 _aComputer Simulation
650 0 4 _aGenetic Association Studies
_xmethods
650 0 4 _aGenetic Predisposition to Disease
_xgenetics
650 0 4 _aGenetic Variation
_xgenetics
650 0 4 _aHumans
650 0 4 _aModels, Genetic
650 0 4 _aProprotein Convertase 9
_xgenetics
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aRisk Factors
650 0 4 _aSequence Analysis, DNA
_xmethods
700 1 _aLu, Wenbin
700 1 _aRotroff, Daniel M
700 1 _aKuenemann, Melaine A
700 1 _aChang, Sheng-Mao
700 1 _aWu, Michael C
700 1 _aWagner, Michael J
700 1 _aBuse, John B
700 1 _aMotsinger-Reif, Alison A
700 1 _aFourches, Denis
700 1 _aTzeng, Jung-Ying
773 0 _tPLoS computational biology
_gvol. 15
_gno. 2
_gp. e1006722
856 4 0 _uhttps://doi.org/10.1371/journal.pcbi.1006722
_zAvailable from publisher's website
999 _c29387902
_d29387902