000 01750 a2200445 4500
005 20250518022121.0
264 0 _c20200618
008 202006s 0 0 eng d
022 _a1468-330X
024 7 _a10.1136/jnnp-2018-319713
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAmmoun, Sylwia
245 0 0 _aPhase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2.
_h[electronic resource]
260 _bJournal of neurology, neurosurgery, and psychiatry
_c10 2019
300 _a1184-1187 p.
_bdigital
500 _aPublication Type: Letter; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAntineoplastic Agents
_xmetabolism
650 0 4 _aBlotting, Western
650 0 4 _aCaspase 3
_xdrug effects
650 0 4 _aCyclin D1
_xdrug effects
650 0 4 _aHumans
650 0 4 _aImmunohistochemistry
650 0 4 _aLeukocytes, Mononuclear
_xdrug effects
650 0 4 _aMitogen-Activated Protein Kinase 1
_xdrug effects
650 0 4 _aMitogen-Activated Protein Kinase 3
_xdrug effects
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aNeurofibromatosis 2
_xdrug therapy
650 0 4 _aProto-Oncogene Proteins c-akt
_xdrug effects
650 0 4 _aReceptor, Platelet-Derived Growth Factor beta
_xdrug effects
650 0 4 _aRibosomal Protein S6
_xdrug effects
650 0 4 _aSorafenib
_xmetabolism
700 1 _aEvans, D Gareth
700 1 _aHilton, David A
700 1 _aStreeter, Adam
700 1 _aHayward, Christopher
700 1 _aHanemann, C Oliver
773 0 _tJournal of neurology, neurosurgery, and psychiatry
_gvol. 90
_gno. 10
_gp. 1184-1187
856 4 0 _uhttps://doi.org/10.1136/jnnp-2018-319713
_zAvailable from publisher's website
999 _c29327978
_d29327978