000 01993 a2200601 4500
005 20250518020229.0
264 0 _c20200507
008 202005s 0 0 eng d
022 _a1554-8635
024 7 _a10.1080/15548627.2019.1569913
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNiu, Chao
245 0 0 _aMetformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway.
_h[electronic resource]
260 _bAutophagy
_c05 2019
300 _a843-870 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAutophagy
_xdrug effects
650 0 4 _aCapillary Permeability
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aDiabetes Mellitus, Experimental
_xcomplications
650 0 4 _aDiabetic Angiopathies
_xmetabolism
650 0 4 _aDown-Regulation
_xdrug effects
650 0 4 _aEndothelium, Vascular
_xdrug effects
650 0 4 _aGene Expression Regulation
_xdrug effects
650 0 4 _aHEK293 Cells
650 0 4 _aHedgehog Proteins
_xdrug effects
650 0 4 _aHuman Umbilical Vein Endothelial Cells
650 0 4 _aHumans
650 0 4 _aHyperglycemia
_xcomplications
650 0 4 _aMetformin
_xpharmacology
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Transgenic
650 0 4 _aRetina
_xdrug effects
650 0 4 _aSignal Transduction
_xdrug effects
700 1 _aChen, Zhiwei
700 1 _aKim, Kyoung Tae
700 1 _aSun, Jia
700 1 _aXue, Mei
700 1 _aChen, Gen
700 1 _aLi, Santie
700 1 _aShen, Yingjie
700 1 _aZhu, Zhongxin
700 1 _aWang, Xu
700 1 _aLiang, Jiaojiao
700 1 _aJiang, Chao
700 1 _aCong, Weitao
700 1 _aJin, Litai
700 1 _aLi, Xiaokun
773 0 _tAutophagy
_gvol. 15
_gno. 5
_gp. 843-870
856 4 0 _uhttps://doi.org/10.1080/15548627.2019.1569913
_zAvailable from publisher's website
999 _c29264280
_d29264280