000 02034 a2200505 4500
005 20250518015635.0
264 0 _c20190521
008 201905s 0 0 eng d
022 _a1476-5594
024 7 _a10.1038/s41388-018-0670-9
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKarvonen, Hanna
245 0 0 _aWnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting.
_h[electronic resource]
260 _bOncogene
_c04 2019
300 _a3288-3300 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAniline Compounds
_xpharmacology
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBridged Bicyclo Compounds, Heterocyclic
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDrug Resistance, Neoplasm
_xgenetics
650 0 4 _aHumans
650 0 4 _aOncogene Proteins, Fusion
_xgenetics
650 0 4 _aPrecursor B-Cell Lymphoblastic Leukemia-Lymphoma
_xdrug therapy
650 0 4 _aPrecursor Cell Lymphoblastic Leukemia-Lymphoma
_xdrug therapy
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xgenetics
650 0 4 _aReceptor Tyrosine Kinase-like Orphan Receptors
_xgenetics
650 0 4 _aSulfonamides
_xpharmacology
650 0 4 _aSurvival Rate
650 0 4 _aTranslocation, Genetic
_xdrug effects
650 0 4 _aUp-Regulation
_xdrug effects
650 0 4 _aWnt Signaling Pathway
_xdrug effects
650 0 4 _aWnt-5a Protein
_xgenetics
650 0 4 _arhoA GTP-Binding Protein
_xgenetics
700 1 _aPerttilä, Robert
700 1 _aNiininen, Wilhelmiina
700 1 _aHautanen, Veera
700 1 _aBarker, Harlan
700 1 _aMurumägi, Astrid
700 1 _aHeckman, Caroline A
700 1 _aUngureanu, Daniela
773 0 _tOncogene
_gvol. 38
_gno. 17
_gp. 3288-3300
856 4 0 _uhttps://doi.org/10.1038/s41388-018-0670-9
_zAvailable from publisher's website
999 _c29242415
_d29242415