| 000 | 01760 a2200469 4500 | ||
|---|---|---|---|
| 005 | 20250518015630.0 | ||
| 264 | 0 | _c20200123 | |
| 008 | 202001s 0 0 eng d | ||
| 022 | _a1521-009X | ||
| 024 | 7 |
_a10.1124/dmd.118.084665 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aItkonen, Matti K | |
| 245 | 0 | 0 |
_aClopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _c04 2019 |
||
| 300 |
_a377-385 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aArea Under Curve |
| 650 | 0 | 4 |
_aAryl Hydrocarbon Hydroxylases _xmetabolism |
| 650 | 0 | 4 |
_aBiotransformation _xphysiology |
| 650 | 0 | 4 |
_aClopidogrel _xpharmacology |
| 650 | 0 | 4 | _aCross-Over Studies |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP2C8 _xmetabolism |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP2C8 Inhibitors _xpoisoning |
| 650 | 0 | 4 |
_aDrug Interactions _xphysiology |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 |
_aGemfibrozil _xpharmacology |
| 650 | 0 | 4 | _aGenotype |
| 650 | 0 | 4 |
_aGlucuronides _xpharmacology |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aHypolipidemic Agents _xpoisoning |
| 650 | 0 | 4 |
_aLoratadine _xanalogs & derivatives |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aYoung Adult |
| 700 | 1 | _aTornio, Aleksi | |
| 700 | 1 | _aNeuvonen, Mikko | |
| 700 | 1 | _aNeuvonen, Pertti J | |
| 700 | 1 | _aNiemi, Mikko | |
| 700 | 1 | _aBackman, Janne T | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 47 _gno. 4 _gp. 377-385 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.118.084665 _zAvailable from publisher's website |
| 999 |
_c29242086 _d29242086 |
||