| 000 | 01529 a2200421 4500 | ||
|---|---|---|---|
| 005 | 20250518015628.0 | ||
| 264 | 0 | _c20200305 | |
| 008 | 202003s 0 0 eng d | ||
| 022 | _a1464-3405 | ||
| 024 | 7 |
_a10.1016/j.bmcl.2018.12.065 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aHe, Lian-Jun | |
| 245 | 0 | 0 |
_aShape-based virtual screen for the discovery of novel CDK8 inhibitor chemotypes. _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry letters _c02 2019 |
||
| 300 |
_a549-555 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 |
_aColorectal Neoplasms _xpathology |
| 650 | 0 | 4 |
_aCyclin-Dependent Kinase 8 _xantagonists & inhibitors |
| 650 | 0 | 4 | _aDrug Discovery |
| 650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
| 650 | 0 | 4 |
_aG1 Phase _xdrug effects |
| 650 | 0 | 4 | _aHCT116 Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMolecular Docking Simulation |
| 650 | 0 | 4 | _aPhosphorylation |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xchemistry |
| 650 | 0 | 4 |
_aS Phase _xdrug effects |
| 650 | 0 | 4 |
_aSTAT1 Transcription Factor _xmetabolism |
| 700 | 1 | _aZhu, Yi-Bao | |
| 700 | 1 | _aFan, Qing-Zhu | |
| 700 | 1 | _aMiao, Dong-Dong | |
| 700 | 1 | _aZhang, Sheng-Peng | |
| 700 | 1 | _aLiu, Xiao-Ping | |
| 700 | 1 | _aZhang, Chao | |
| 773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 29 _gno. 4 _gp. 549-555 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2018.12.065 _zAvailable from publisher's website |
| 999 |
_c29241991 _d29241991 |
||