000			02045 a2200601 4500
005			20250518014554.0
264		0	_c20200413
008			202004s 0 0 eng d
022			_a1559-2030
024	7		_a10.1016/j.cct.2018.12.012 _2doi
040			_aNLM _beng _cNLM
100	1		_aSorkness, Christine A
245	0	0	_aAdapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era. _h[electronic resource]
260			_bContemporary clinical trials _c02 2019
300			_a98-103 p. _bdigital
500			_aPublication Type: Clinical Trial Protocol; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAdult
650	0	4	_aFemale
650	0	4	_aHumans
650	0	4	_aMale
650	0	4	_aMiddle Aged
650	0	4	_aAdministration, Inhalation
650	0	4	_aAdrenal Cortex Hormones _xadministration & dosage
650	0	4	_aAnti-Asthmatic Agents _xtherapeutic use
650	0	4	_aAsthma _xdrug therapy
650	0	4	_aBiomarkers
650	0	4	_aDouble-Blind Method
650	0	4	_aEosinophilia _xepidemiology
650	0	4	_aPhenotype
650	0	4	_aPrecision Medicine _xmethods
650	0	4	_aResearch Design
650	0	4	_aSputum _ximmunology
650	0	4	_aRandomized Controlled Trials as Topic
650	0	4	_aMulticenter Studies as Topic
700	1		_aKing, Tonya S
700	1		_aDyer, Anne-Marie
700	1		_aChinchilli, Vernon M
700	1		_aMauger, David T
700	1		_aKrishnan, Jerry A
700	1		_aBlake, Kathryn
700	1		_aCastro, Mario
700	1		_aCovar, Ronina
700	1		_aIsrael, Elliot
700	1		_aKraft, Monica
700	1		_aLang, Jason E
700	1		_aLugogo, Njira
700	1		_aPeters, Stephen P
700	1		_aWechsler, Michael E
700	1		_aWenzel, Sally E
700	1		_aLazarus, Stephen C
773	0		_tContemporary clinical trials _gvol. 77 _gp. 98-103
856	4	0	_uhttps://doi.org/10.1016/j.cct.2018.12.012 _zAvailable from publisher's website
999			_c29205986 _d29205986