000 | 01671 a2200481 4500 | ||
---|---|---|---|
005 | 20250518012112.0 | ||
264 | 0 | _c20181224 | |
008 | 201812s 0 0 eng d | ||
022 | _a1347-5223 | ||
024 | 7 |
_a10.1248/cpb.c18-00571 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aMorishita, Ko | |
245 | 0 | 0 |
_a2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives: Mixed-Type PTP1B Inhibitors without PPARγ Activation. _h[electronic resource] |
260 |
_bChemical & pharmaceutical bulletin _c2018 |
||
300 |
_a1131-1152 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aDiabetes Mellitus, Experimental _xdrug therapy |
650 | 0 | 4 | _aDose-Response Relationship, Drug |
650 | 0 | 4 |
_aEnzyme Inhibitors _xblood |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aHypoglycemic Agents _xblood |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aMice, Inbred Strains |
650 | 0 | 4 | _aMolecular Docking Simulation |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 |
_aPPAR gamma _xmetabolism |
650 | 0 | 4 |
_aProtein Tyrosine Phosphatase, Non-Receptor Type 1 _xantagonists & inhibitors |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aRats, Sprague-Dawley |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aTetrahydroisoquinolines _xblood |
700 | 1 | _aShoji, Yoshimichi | |
700 | 1 | _aFukui, Masaki | |
700 | 1 | _aIto, Yuma | |
700 | 1 | _aKitao, Tatsuya | |
700 | 1 | _aOzawa, Shin-Ichiro | |
700 | 1 | _aHirono, Shuichi | |
700 | 1 | _aShirahase, Hiroaki | |
773 | 0 |
_tChemical & pharmaceutical bulletin _gvol. 66 _gno. 12 _gp. 1131-1152 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1248/cpb.c18-00571 _zAvailable from publisher's website |
999 |
_c29118542 _d29118542 |