000 01342 a2200385 4500
005 20250518010636.0
264 0 _c20191213
008 201912s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/s41598-018-35189-7
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aScarneo, Scott A
245 0 0 _aGenetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion.
_h[electronic resource]
260 _bScientific reports
_c11 2018
300 _a17058 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAnimals
650 0 4 _aFemale
650 0 4 _aMAP Kinase Kinase Kinases
_xgenetics
650 0 4 _aMacrophages
_xdrug effects
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aTumor Necrosis Factor-alpha
_xmetabolism
700 1 _aMansourati, Antoine
700 1 _aEibschutz, Liesl S
700 1 _aTotzke, Juliane
700 1 _aRoques, Jose R
700 1 _aLoiselle, David
700 1 _aCarlson, David
700 1 _aHughes, Philip
700 1 _aHaystead, Timothy A J
773 0 _tScientific reports
_gvol. 8
_gno. 1
_gp. 17058
856 4 0 _uhttps://doi.org/10.1038/s41598-018-35189-7
_zAvailable from publisher's website
999 _c29067004
_d29067004