000 01479 a2200397 4500
005 20250518010519.0
264 0 _c20190618
008 201906s 0 0 eng d
022 _a1096-7184
024 7 _a10.1016/j.ymben.2018.11.003
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKim, Che Lin
245 0 0 _aImproving recombinant bone morphogenetic protein-4 (BMP-4) production by autoregulatory feedback loop removal using BMP receptor-knockout CHO cell lines.
_h[electronic resource]
260 _bMetabolic engineering
_c03 2019
300 _a57-67 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntimetabolites
_xpharmacology
650 0 4 _aBone Morphogenetic Protein 4
_xbiosynthesis
650 0 4 _aBone Morphogenetic Protein Receptors
_xantagonists & inhibitors
650 0 4 _aCHO Cells
650 0 4 _aCRISPR-Cas Systems
650 0 4 _aCricetinae
650 0 4 _aCricetulus
650 0 4 _aFeedback, Physiological
650 0 4 _aGene Expression Profiling
650 0 4 _aGene Knockout Techniques
650 0 4 _aHomeostasis
650 0 4 _aMethotrexate
_xpharmacology
650 0 4 _aPyrazoles
_xpharmacology
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aRecombinant Proteins
700 1 _aLee, Gyun Min
773 0 _tMetabolic engineering
_gvol. 52
_gp. 57-67
856 4 0 _uhttps://doi.org/10.1016/j.ymben.2018.11.003
_zAvailable from publisher's website
999 _c29062505
_d29062505