000 02228 a2200613 4500
005 20250518010403.0
264 0 _c20181219
008 201812s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/s41467-018-07071-7
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aVillahoz, Silvia
245 0 0 _aConditional deletion of Rcan1 predisposes to hypertension-mediated intramural hematoma and subsequent aneurysm and aortic rupture.
_h[electronic resource]
260 _bNature communications
_c11 2018
300 _a4795 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAortic Dissection
_xgenetics
650 0 4 _aAnimals
650 0 4 _aAntihypertensive Agents
_xpharmacology
650 0 4 _aAorta
_xdrug effects
650 0 4 _aAortic Rupture
_xgenetics
650 0 4 _aCalcium-Binding Proteins
650 0 4 _aDisease Models, Animal
650 0 4 _aEndothelial Cells
_xdrug effects
650 0 4 _aGene Deletion
650 0 4 _aGene Expression Regulation
650 0 4 _aGenetic Predisposition to Disease
650 0 4 _aGlycogen Synthase Kinase 3 beta
_xantagonists & inhibitors
650 0 4 _aHematoma
_xgenetics
650 0 4 _aHumans
650 0 4 _aHypertension
_xdrug therapy
650 0 4 _aIntracellular Signaling Peptides and Proteins
_xdeficiency
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aMuscle Proteins
_xdeficiency
650 0 4 _aMyocytes, Smooth Muscle
_xdrug effects
650 0 4 _aPrimary Cell Culture
650 0 4 _aProtein Isoforms
_xdeficiency
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _arho-Associated Kinases
_xantagonists & inhibitors
700 1 _aYunes-Leites, Paula Sofía
700 1 _aMéndez-Barbero, Nerea
700 1 _aUrso, Katia
700 1 _aBonzon-Kulichenko, Elena
700 1 _aOrtega, Sagrario
700 1 _aNistal, J Francisco
700 1 _aVazquez, Jesus
700 1 _aOffermanns, Stefan
700 1 _aRedondo, Juan Miguel
700 1 _aCampanero, Miguel R
773 0 _tNature communications
_gvol. 9
_gno. 1
_gp. 4795
856 4 0 _uhttps://doi.org/10.1038/s41467-018-07071-7
_zAvailable from publisher's website
999 _c29058162
_d29058162