000 02337 a2200649 4500
005 20250518005606.0
264 0 _c20190422
008 201904s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/s41467-018-07188-9
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHan, Fei
245 0 0 _aThe critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance.
_h[electronic resource]
260 _bNature communications
_c11 2018
300 _a4728 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdenylate Kinase
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aCalcium
_xmetabolism
650 0 4 _aCalcium-Calmodulin-Dependent Protein Kinase Kinase
_xmetabolism
650 0 4 _aCarcinogenesis
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Movement
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aDisease Progression
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aEnzyme Activation
_xdrug effects
650 0 4 _aEpidermal Growth Factor
_xpharmacology
650 0 4 _aErbB Receptors
_xmetabolism
650 0 4 _aFibroblasts
_xdrug effects
650 0 4 _aGlycolysis
_xdrug effects
650 0 4 _aHuman Umbilical Vein Endothelial Cells
_xmetabolism
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aNeovascularization, Pathologic
_xpathology
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aPhosphoserine
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
_xmetabolism
650 0 4 _aS-Phase Kinase-Associated Proteins
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aStress, Physiological
_xdrug effects
650 0 4 _aUbiquitination
_xdrug effects
700 1 _aLi, Chien-Feng
700 1 _aCai, Zhen
700 1 _aZhang, Xian
700 1 _aJin, Guoxiang
700 1 _aZhang, Wei-Na
700 1 _aXu, Chuan
700 1 _aWang, Chi-Yun
700 1 _aMorrow, John
700 1 _aZhang, Shuxing
700 1 _aXu, Dazhi
700 1 _aWang, Guihua
700 1 _aLin, Hui-Kuan
773 0 _tNature communications
_gvol. 9
_gno. 1
_gp. 4728
856 4 0 _uhttps://doi.org/10.1038/s41467-018-07188-9
_zAvailable from publisher's website
999 _c29029458
_d29029458