| 000 | 01848 a2200517 4500 | ||
|---|---|---|---|
| 005 | 20250518005058.0 | ||
| 264 | 0 | _c20191028 | |
| 008 | 201910s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/acs.jmedchem.8b01259 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aNaylor, Matthew R | |
| 245 | 0 | 0 |
_aLipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _c12 2018 |
||
| 300 |
_a11169-11182 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_a1-Octanol _xchemistry |
| 650 | 0 | 4 |
_aCell Membrane Permeability _xdrug effects |
| 650 | 0 | 4 |
_aCyclosporins _xchemistry |
| 650 | 0 | 4 | _aHydrogen Bonding |
| 650 | 0 | 4 | _aHydrophobic and Hydrophilic Interactions |
| 650 | 0 | 4 |
_aPeptides _xchemistry |
| 650 | 0 | 4 |
_aPeptides, Cyclic _xchemistry |
| 650 | 0 | 4 |
_aPharmaceutical Preparations _xchemistry |
| 650 | 0 | 4 |
_aSmall Molecule Libraries _xchemistry |
| 650 | 0 | 4 | _aSolubility |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aWater _xchemistry |
| 700 | 1 | _aLy, Andrew M | |
| 700 | 1 | _aHandford, Mason J | |
| 700 | 1 | _aRamos, Daniel P | |
| 700 | 1 | _aPye, Cameron R | |
| 700 | 1 | _aFurukawa, Akihiro | |
| 700 | 1 | _aKlein, Victoria G | |
| 700 | 1 | _aNoland, Ryan P | |
| 700 | 1 | _aEdmondson, Quinn | |
| 700 | 1 | _aTurmon, Alexandra C | |
| 700 | 1 | _aHewitt, William M | |
| 700 | 1 | _aSchwochert, Joshua | |
| 700 | 1 | _aTownsend, Chad E | |
| 700 | 1 | _aKelly, Colin N | |
| 700 | 1 | _aBlanco, Maria-Jesus | |
| 700 | 1 | _aLokey, R Scott | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 61 _gno. 24 _gp. 11169-11182 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.8b01259 _zAvailable from publisher's website |
| 999 |
_c29012065 _d29012065 |
||