000 01766 a2200469 4500
005 20250518004531.0
264 0 _c20191014
008 201910s 0 0 eng d
022 _a1573-8744
024 7 _a10.1007/s10928-018-9609-6
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBiliouris, Konstantinos
245 0 0 _aA pre-clinical quantitative model predicts the pharmacokinetics/pharmacodynamics of an anti-BDCA2 monoclonal antibody in humans.
_h[electronic resource]
260 _bJournal of pharmacokinetics and pharmacodynamics
_c12 2018
300 _a817-827 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntibodies, Monoclonal, Humanized
_xpharmacology
650 0 4 _aBody Weight
650 0 4 _aComputer Simulation
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aHumans
650 0 4 _aImmunoglobulin G
650 0 4 _aLectins, C-Type
_xantagonists & inhibitors
650 0 4 _aLupus Erythematosus, Cutaneous
_xdrug therapy
650 0 4 _aLupus Erythematosus, Systemic
_xdrug therapy
650 0 4 _aMacaca fascicularis
650 0 4 _aMembrane Glycoproteins
_xantagonists & inhibitors
650 0 4 _aModels, Biological
650 0 4 _aReceptors, Immunologic
_xantagonists & inhibitors
700 1 _aNestorov, Ivan
700 1 _aNaik, Himanshu
700 1 _aDai, David
700 1 _aXiao, Guangqing
700 1 _aWang, Qin
700 1 _aPellerin, Alex
700 1 _aRabah, Dania
700 1 _aLesko, Lawrence J
700 1 _aTrame, Mirjam N
773 0 _tJournal of pharmacokinetics and pharmacodynamics
_gvol. 45
_gno. 6
_gp. 817-827
856 4 0 _uhttps://doi.org/10.1007/s10928-018-9609-6
_zAvailable from publisher's website
999 _c28994631
_d28994631