000			01971 a2200517 4500
005			20250518003300.0
264		0	_c20200304
008			202003s 0 0 eng d
022			_a1432-0738
024	7		_a10.1007/s00204-018-2334-5 _2doi
040			_aNLM _beng _cNLM
100	1		_aLiao, Qiwen
245	0	0	_aNovel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish. _h[electronic resource]
260			_bArchives of toxicology _c01 2019
300			_a189-206 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAmino Acid Sequence
650	0	4	_aAnimals
650	0	4	_aAnthozoa _xchemistry
650	0	4	_aAnticonvulsants _xpharmacology
650	0	4	_aHeme Oxygenase (Decyclizing) _xmetabolism
650	0	4	_aLocomotion
650	0	4	_aMolecular Docking Simulation
650	0	4	_aMolecular Dynamics Simulation
650	0	4	_aNeuroprotective Agents _xpharmacology
650	0	4	_aNitric Oxide Synthase Type II _xmetabolism
650	0	4	_aOxidopamine _xadverse effects
650	0	4	_aPC12 Cells
650	0	4	_aPentylenetetrazole _xadverse effects
650	0	4	_aPeptides _xchemical synthesis
650	0	4	_aProtein Structure, Tertiary
650	0	4	_aRats
650	0	4	_aReactive Oxygen Species _xmetabolism
650	0	4	_aVoltage-Gated Sodium Channel Blockers _xpharmacology
650	0	4	_aVoltage-Gated Sodium Channels _xmetabolism
650	0	4	_aZebrafish
700	1		_aLi, Shengnan
700	1		_aSiu, Shirley Weng In
700	1		_aMorlighem, Jean-Étienne R L
700	1		_aWong, Clarence Tsun Ting
700	1		_aWang, Xiufen
700	1		_aRádis-Baptista, Gandhi
700	1		_aLee, Simon Ming-Yuen
773	0		_tArchives of toxicology _gvol. 93 _gno. 1 _gp. 189-206
856	4	0	_uhttps://doi.org/10.1007/s00204-018-2334-5 _zAvailable from publisher's website
999			_c28951853 _d28951853