| 000 | 02561 a2200709 4500 | ||
|---|---|---|---|
| 005 | 20250517235953.0 | ||
| 264 | 0 | _c20190617 | |
| 008 | 201906s 0 0 eng d | ||
| 022 | _a1474-5488 | ||
| 024 | 7 |
_a10.1016/S1470-2045(18)30497-2 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aDummer, Reinhard | |
| 245 | 0 | 0 |
_aOverall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial. _h[electronic resource] |
| 260 |
_bThe Lancet. Oncology _c10 2018 |
||
| 300 |
_a1315-1327 p. _bdigital |
||
| 500 | _aPublication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aAged |
| 650 | 0 | 4 | _aAged, 80 and over |
| 650 | 0 | 4 |
_aAntineoplastic Combined Chemotherapy Protocols _xadverse effects |
| 650 | 0 | 4 |
_aBenzimidazoles _xadministration & dosage |
| 650 | 0 | 4 |
_aBiomarkers, Tumor _xgenetics |
| 650 | 0 | 4 |
_aCarbamates _xadministration & dosage |
| 650 | 0 | 4 | _aDisease Progression |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aGenetic Predisposition to Disease |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMelanoma _xdrug therapy |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 | _aPhenotype |
| 650 | 0 | 4 | _aProgression-Free Survival |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xadministration & dosage |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins B-raf _xgenetics |
| 650 | 0 | 4 |
_aSkin Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aSulfonamides _xadministration & dosage |
| 650 | 0 | 4 | _aTime Factors |
| 650 | 0 | 4 |
_aVemurafenib _xadministration & dosage |
| 650 | 0 | 4 | _aYoung Adult |
| 700 | 1 | _aAscierto, Paolo A | |
| 700 | 1 | _aGogas, Helen J | |
| 700 | 1 | _aArance, Ana | |
| 700 | 1 | _aMandala, Mario | |
| 700 | 1 | _aLiszkay, Gabriella | |
| 700 | 1 | _aGarbe, Claus | |
| 700 | 1 | _aSchadendorf, Dirk | |
| 700 | 1 | _aKrajsova, Ivana | |
| 700 | 1 | _aGutzmer, Ralf | |
| 700 | 1 | _aChiarion Sileni, Vanna | |
| 700 | 1 | _aDutriaux, Caroline | |
| 700 | 1 | _ade Groot, Jan Willem B | |
| 700 | 1 | _aYamazaki, Naoya | |
| 700 | 1 | _aLoquai, Carmen | |
| 700 | 1 | _aMoutouh-de Parseval, Laure A | |
| 700 | 1 | _aPickard, Michael D | |
| 700 | 1 | _aSandor, Victor | |
| 700 | 1 | _aRobert, Caroline | |
| 700 | 1 | _aFlaherty, Keith T | |
| 773 | 0 |
_tThe Lancet. Oncology _gvol. 19 _gno. 10 _gp. 1315-1327 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/S1470-2045(18)30497-2 _zAvailable from publisher's website |
| 999 |
_c28839727 _d28839727 |
||