000 01486 a2200445 4500
005 20250517234817.0
264 0 _c20190124
008 201901s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/s41467-018-05769-2
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSchiebel, Johannes
245 0 0 _aIntriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes.
_h[electronic resource]
260 _bNature communications
_c09 2018
300 _a3559 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aBenzamidines
_xpharmacology
650 0 4 _aComputer Simulation
650 0 4 _aCrystallography
650 0 4 _aCrystallography, X-Ray
650 0 4 _aHydrogen Bonding
650 0 4 _aLigands
650 0 4 _aNeutron Diffraction
650 0 4 _aProtein Binding
650 0 4 _aSerine Proteinase Inhibitors
_xpharmacology
650 0 4 _aThermodynamics
650 0 4 _aTrypsin
_xchemistry
650 0 4 _aWater
700 1 _aGaspari, Roberto
700 1 _aWulsdorf, Tobias
700 1 _aNgo, Khang
700 1 _aSohn, Christian
700 1 _aSchrader, Tobias E
700 1 _aCavalli, Andrea
700 1 _aOstermann, Andreas
700 1 _aHeine, Andreas
700 1 _aKlebe, Gerhard
773 0 _tNature communications
_gvol. 9
_gno. 1
_gp. 3559
856 4 0 _uhttps://doi.org/10.1038/s41467-018-05769-2
_zAvailable from publisher's website
999 _c28798643
_d28798643