000 02806 a2200877 4500
005 20250517234238.0
264 0 _c20191011
008 201910s 0 0 eng d
022 _a1946-6242
024 7 _a10.1126/scitranslmed.aam6474
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKing, Andrew J
245 0 0 _aInhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability.
_h[electronic resource]
260 _bScience translational medicine
_c08 2018
500 _aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAnimals
650 0 4 _aBase Sequence
650 0 4 _aCell Membrane Permeability
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aElectric Impedance
650 0 4 _aEpithelium
_xmetabolism
650 0 4 _aFemale
650 0 4 _aGastrointestinal Tract
_xmetabolism
650 0 4 _aHealthy Volunteers
650 0 4 _aHumans
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aIntestinal Absorption
_xdrug effects
650 0 4 _aIons
_xurine
650 0 4 _aIsoquinolines
_xpharmacology
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMiddle Aged
650 0 4 _aPhosphates
_xmetabolism
650 0 4 _aPotassium
_xmetabolism
650 0 4 _aProtons
650 0 4 _aRats
650 0 4 _aSodium
_xmetabolism
650 0 4 _aSodium-Hydrogen Exchanger 3
_xantagonists & inhibitors
650 0 4 _aSulfonamides
_xpharmacology
650 0 4 _aTight Junction Proteins
_xmetabolism
650 0 4 _aYoung Adult
700 1 _aSiegel, Matthew
700 1 _aHe, Ying
700 1 _aNie, Baoming
700 1 _aWang, Ji
700 1 _aKoo-McCoy, Samantha
700 1 _aMinassian, Natali A
700 1 _aJafri, Qumber
700 1 _aPan, Deng
700 1 _aKohler, Jill
700 1 _aKumaraswamy, Padmapriya
700 1 _aKozuka, Kenji
700 1 _aLewis, Jason G
700 1 _aDragoli, Dean
700 1 _aRosenbaum, David P
700 1 _aO'Neill, Debbie
700 1 _aPlain, Allein
700 1 _aGreasley, Peter J
700 1 _aJönsson-Rylander, Ann-Cathrine
700 1 _aKarlsson, Daniel
700 1 _aBehrendt, Margareta
700 1 _aStrömstedt, Maria
700 1 _aRyden-Bergsten, Tina
700 1 _aKnöpfel, Thomas
700 1 _aPastor Arroyo, Eva M
700 1 _aHernando, Nati
700 1 _aMarks, Joanne
700 1 _aDonowitz, Mark
700 1 _aWagner, Carsten A
700 1 _aAlexander, R Todd
700 1 _aCaldwell, Jeremy S
773 0 _tScience translational medicine
_gvol. 10
_gno. 456
856 4 0 _uhttps://doi.org/10.1126/scitranslmed.aam6474
_zAvailable from publisher's website
999 _c28779328
_d28779328