000 02227 a2200601 4500
005 20250517234231.0
264 0 _c20190114
008 201901s 0 0 eng d
022 _a1744-8069
024 7 _a10.1177/1744806918801224
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLee, Wan-Hung
245 0 0 _aZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability.
_h[electronic resource]
260 _bMolecular pain
_c
300 _a1744806918801224 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdaptor Proteins, Signal Transducing
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aAnimals, Newborn
650 0 4 _aAntineoplastic Agents
_xadverse effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aCerebral Cortex
_xcytology
650 0 4 _aDisease Models, Animal
650 0 4 _aEnzyme Inhibitors
_xtherapeutic use
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aGreen Fluorescent Proteins
_xgenetics
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aHyperalgesia
_xdrug therapy
650 0 4 _aImmunoprecipitation
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aNeuralgia
_xchemically induced
650 0 4 _aNeurons
650 0 4 _aNitric Oxide Synthase Type I
_xantagonists & inhibitors
650 0 4 _aPaclitaxel
_xadverse effects
650 0 4 _aPain Threshold
_xdrug effects
650 0 4 _aRats
650 0 4 _aTransfection
650 0 4 _aXenograft Model Antitumor Assays
_xmethods
700 1 _aCarey, Lawrence M
700 1 _aLi, Li-Li
700 1 _aXu, Zhili
700 1 _aLai, Yvonne Y
700 1 _aCourtney, Michael J
700 1 _aHohmann, Andrea G
773 0 _tMolecular pain
_gvol. 14
_gp. 1744806918801224
856 4 0 _uhttps://doi.org/10.1177/1744806918801224
_zAvailable from publisher's website
999 _c28778887
_d28778887