000 01616 a2200481 4500
005 20250517233836.0
264 0 _c20190522
008 201905s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2018.08.015
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMcGowan, David C
245 0 0 _aDesign and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_c10 2018
300 _a3216-3221 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aDrug Design
650 0 4 _aMice
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aStructure-Activity Relationship
650 0 4 _aToll-Like Receptor 7
_xagonists
650 0 4 _aToll-Like Receptor 8
_xagonists
700 1 _aHerschke, Florence
700 1 _aKhamlichi, Mourad D
700 1 _aRosauro, Mari Luz
700 1 _aBenedicto, Sara M Pérez
700 1 _aPauwels, Frederik
700 1 _aStoops, Bart
700 1 _aPande, Vineet
700 1 _aScholliers, Annick
700 1 _aVan Schoubroeck, Bertrand
700 1 _aMostmans, Wendy
700 1 _aVan Dijck, Kris
700 1 _aThoné, Tine
700 1 _aHorton, Helen
700 1 _aFanning, Gregory
700 1 _aJonckers, Tim H M
700 1 _aRaboisson, Pierre
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 28
_gno. 19
_gp. 3216-3221
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2018.08.015
_zAvailable from publisher's website
999 _c28764866
_d28764866