000 02056 a2200565 4500
005 20250517230037.0
264 0 _c20181212
008 201812s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/s41467-018-05013-x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKundu, Samrat T
245 0 0 _aTMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.
_h[electronic resource]
260 _bNature communications
_c07 2018
300 _a2731 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdenocarcinoma of Lung
_xdrug therapy
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBasic Helix-Loop-Helix Leucine Zipper Transcription Factors
_xgenetics
650 0 4 _aCalcium
_xmetabolism
650 0 4 _aCathepsins
_xantagonists & inhibitors
650 0 4 _aCell Line, Tumor
650 0 4 _aCysteine Proteinase Inhibitors
_xpharmacology
650 0 4 _aExocytosis
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aHumans
650 0 4 _aLeucine
_xanalogs & derivatives
650 0 4 _aLung Neoplasms
_xdrug therapy
650 0 4 _aLysosomes
_xdrug effects
650 0 4 _aMembrane Proteins
_xgenetics
650 0 4 _aMice
650 0 4 _aNeoplasm Metastasis
650 0 4 _aNerve Tissue Proteins
_xgenetics
650 0 4 _aPrognosis
650 0 4 _aProtein Isoforms
_xgenetics
650 0 4 _aProteolysis
650 0 4 _aSignal Transduction
650 0 4 _aSurvival Analysis
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aGrzeskowiak, Caitlin L
700 1 _aFradette, Jared J
700 1 _aGibson, Laura A
700 1 _aRodriguez, Leticia B
700 1 _aCreighton, Chad J
700 1 _aScott, Kenneth L
700 1 _aGibbons, Don L
773 0 _tNature communications
_gvol. 9
_gno. 1
_gp. 2731
856 4 0 _uhttps://doi.org/10.1038/s41467-018-05013-x
_zAvailable from publisher's website
999 _c28637289
_d28637289